General Considerations Page: 1 of 20
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? The following is a rc.ort ce rta in Aolo ii tets -hich
we have pcrforaed on a compound received from you, marked
SOLVIT, and which has the following structural formula:
c,(CC) CHG:CH(C),COG}-!C .CEn fc,-00-!CC-CO
M3)-CHs
General Considerations
In investigating possible deleterious effects of Solvit t;
have followed essentially the procedure previously epl yed in
our study of the utilization of polglycerol esters (C. Bodansky,
C.L. Herrmann and K. Ca pbell, B:iochnsa. J. 32: 1938, 1938). 1
believe it is safe to assne that a fat%-lie coo und of the
type of lvit may be considered ,ith ou hazard to health if the
f ollowi>g c. ditions are set:
1. en fed at a high level as a supplement to a basal diet
the effects differ in no essential manner fr those obtained
when the dietary sui2laaent consists of a fat such as lard, Liven
in the seue amont.
2. Growth of rats must be the same in the experimental (Solvet
rats) as in the controls (lard-fed).
3. productive success must confor- to nor al standards and
be similar in the two groups of animals.
4. Lactation aust be at least just as successful in the test
animals as in the controls.
5. The offsprind of the test ani Is aust be reared to the
point a eaning ile the mothers are maintained on a diet
containinL I0 per cent of the test substance (Solvit), and,
subse, uently, these same offsprin- , ast be reared to :aurity on
the s ae diet.A
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General Considerations, report, 1939-01-16/1939-09-30; (https://texashistory.unt.edu/ark:/67531/metapth228755/m1/1/: accessed June 13, 2024), University of North Texas Libraries, The Portal to Texas History, https://texashistory.unt.edu; crediting Moody Medical Library, UT.